Abnormal Circle of Willis among Migraineurs in Sudan
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چکیده
Migraine has been connected to hypoperfusion and cerebral ischemia in several studies [1,2]. Moreover, increased prevalence of silent white mater changes and even minute cerebral infarcts is reported in migraineurs [1]. Cucchiara and Detre proposed that migraine can cause or result from cerebral ischemia [3]. The basis of their assumption emerged from observations that catheter angiography can cause irritation of the endothelial and this may trigger cortical spreading depression (CSD) and eventually migraine attack [4]. Hence, characteristic blood flow changes in CSD which include aninitial transient increased blood flow followed by a longer period of hypoperfusion might precipitate cerebral ischemia in some cases. The altered blood flow changes are thought to occur during the migraine aura [5], and demonstrated during headache in patients with migraine without aura as well [6].
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تاریخ انتشار 2017